The Thermo Scientific picoSpin 45 NMR spectrometer is a useful tool for teaching through the aldol condensation reaction. In a number of undergraduate organic teaching programs, probably the first ...
Organic synthesis is based on carbon-carbon bond formation. Aldol condensation is one of the key reactions, forming a new β-hydroxy carbonyl compound through the reaction of two carbonyl compounds.
The protocol for the preparation of boron enolates and their subsequent reaction with aldehydes is described, providing convenient access to β-hydroxy ketones in good yields and with high ...